Browsing by Subject "MACS"
Now showing items 1-2 of 2
-
Novel mitochondrial and cytosolic purification pipeline for compartment-specific metabolomics in mammalian disease model tissues
(Springer, 2020)Introduction Mitochondria represent an important milieu for studying the pathogenesis of several major diseases. The need for organelle-level metabolic resolution exists, as mitochondrial/cytosolic metabolites are often ... -
Sub-cellular metabolomics investigation of mitochondrial CI deficiency in cytosol & mitochondria of Ndufs4 mice
(North-West University (South Africa), 2022)Mitochondrial Complex I (CI) is regarded as the foremost entry point for electrons that fuel oxidative phosphorylation. CI deficiency (CID) is the most common mitochondrial disease (MD) in humans and Leigh syndrome (LS), ...
