Browsing by Subject "Intercellular messenger"

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Transmission of clinical risk factors through circulating DNA

Aucamp, Janine (North-West University (South Africa), Potchefstroom Campus, 2017)

Newly synthesised, actively released circulating DNA can translocate to neighbouring and remote parts of the body, enter cells and alter their biology. It has been implicated in the bystander effect, tumour development ...
Valproic acid alters the content and function of the cell-free DNA released by hepatocellular carcinoma (HepG2) cells in vitro

Aucamp, Janine; Van Dyk, Hayley C.; Bronkhorst, Abel J.; Pretorius, Piet J. (Elsevier, 2017)

Background It has long been believed that cell-free DNA (cfDNA) actively released into circulation can serve as intercellular messengers, and their involvement in processes such as the bystander effect strongly support ...