Now showing items 1-2 of 2

    • 2-Heteroarylidene-1-indanone derivatives as inhibitors of monoamine oxidase 

      Nel, Magdalena S.; Petzer, Anél; Petzer, Jacobus P.; Legoabe, Lesetja J. (Elsevier, 2016)
      In the present study a series of fifteen 2-heteroarylidene-1-indanone derivatives were synthesised and evaluated as inhibitors of recombinant human monoamine oxidase (MAO) A and B. These compounds are structurally related ...
    • Monoamine oxidase inhibition by indanone and benzoquinone analogues 

      Mostert, Samantha (North-West University (South Africa) , Potchefstroom Campus, 2015)
      Parkinson’s disease (PD) is a neurological disorder of which aging is the greatest risk factor. Over the next fifteen years, the number of persons affected by PD worldwide is expected to increase from 4.6 million to 9.3 ...