Browsing by Subject "Glutathione peroxidase"
Now showing items 1-6 of 6
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Antioxidant enzyme activity is associated with blood pressure and carotid intima media thickness in black men and women: the SABPA study
(Elsevier, 2016)In the urbanized black population of South Africa, oxidative stress may play a crucial role in the development of hypertension. Since oxidative stress may result from impaired antioxidant capacity we aimed to investigate ... -
The association of measures of the micro- and macro-vasculature with selenium and GPx activity in a young bi-ethnic population: the African-PREDICT study
(Taylor & Francis, 2019)Objective: Selenium plays an important physiological role as component for antioxidant selenoproteins such as glutathione peroxidase (GPx). Since oxidative stress contributes to hypertension development, it is likely that ... -
The relationship of nitric oxide synthesis capacity, oxidative stress, and albumin-to-creatinine ratio in black and white men: the SABPA study
(Springer, 2016)Inadequate substrate availability and increased nitric oxide synthase inhibitor levels attenuate nitric oxide (NO) synthesis, whereas increased vascular oxidative stress may lead to inactivation of NO. We compared markers ... -
Serum selenium levels, the selenoprotein glutathione peroxidase and vascular protection: the SABPA study
(Elsevier, 2018)Selenium is an important co-factor for the optimal functioning of the antioxidant enzyme, glutathione peroxidase (GPx). Studies investigating the associations of selenium with blood pressure (BP) and hemodynamic measures ... -
The association of oxidative stress with arterial compliance and vascular resistance in a bi-ethnic population: the SABPA study
(Taylor & Francis Ltd, 2016)A loss of arterial elasticity increases the risk for cardiovascular events. Oxidative injury to the vessel wall may be one of the underlying mechanisms influencing arterial elasticity. We compared markers of oxidative ... -
Three-year change in oxidative stress markers is linked to target organ damage in black and white men: the SABPA study
(Springer, 2019)Oxidative stress is implicated in hypertension, carotid wall thickening, and renal dysfunction. Oxidative stress is linked to cardiovascular pathology in the black South African individuals who have a high prevalence of ...