Browsing by Subject "GLYAT"
Now showing items 1-5 of 5
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Cloning and expression of human recombinant isoform a of glycine–N–acyltransferase
(North-West University, 2012)Awareness of detoxification, nowadays known as biotransformation, has become an integral part of our daily lives. It is a modern buzz word that is used to promote anything from health food to enhancement of performance in ... -
Glycine conjugation: importance in metabolism, the role of glycine N-acyltransferase, and factors that influence interindividual variation
(Taylor & Francis, 2013)Introduction: Glycine conjugation of mitochondrial acyl-CoAs, catalyzed by glycine N-acyltransferase (GLYAT, E.C. 2.3.1.13), is an important metabolic pathway responsible for maintaining adequate levels of free coenzyme A ... -
Investigation and characterisation of the genetic variation in the coding region of the glycine N-acyltransferase gene
(North-West University, 2015)Thorough investigation of the glycine conjugation pathway has been neglected over the last 30 years. Environmental factors, nutrition, and the chronic use of medications are increasing the exposure of humans to benzoate ... -
A new perspective on the importance of glycine N–acyltransferase in the detoxification of benzoic acid
(2014)Despite being the first biochemical reaction to be discovered, the glycine conjugation pathway remains poorly characterised. It has generally been assumed that glycine conjugation serves to increase the water solubility ... -
Sequencing and molecular characterization of variations in the glycine N–acyltransferase gene
(2014)Humans are continuously challenged by harmful endogenous and xenobiotic substances. Detoxification is the ability to neutralise and remove these substances from the body. Glycine N-acyltransferase, EC 2.3.1.13 (GLYAT) is ...
