Now showing items 1-3 of 3

    • The dilemma of diagnosing coenzyme Q10 deficiency in muscle 

      Louw, Roan; Wilsenach, Kimmey-Li; Jonck, Lindi-Maryn; Schoonen, Maryke; Van der Westhuizen, Francois H. (Elsevier, 2018)
      Background Coenzyme Q10 (CoQ10) is an important component of the mitochondrial respiratory chain (RC) and is critical for energy production. Although the prevalence of CoQ10 deficiency is still unknown, the general consensus ...
    • Establishing the comet assay to determine the effects of different perturbations on DNA repair capacity 

      Steenkamp, Anzaan (North-West University, 2011)
      Single cell gel electrophoresis (SCGE), more commonly known as the Comet assay, is an uncomplicated, affordable and versatile method for investigating DNA damage and repair. Existing comet–assay based methods were modified ...
    • Evaluation of ROS production in OXPHOS knockout strains of C. elegans 

      Dreyer, Chantell (North-West University (South Africa), 2024-06)
      The oxidative phosphorylation (OXPHOS) system, comprising five complexes, regulates electron transport and adenosine triphosphate (ATP) synthesis in mitochondria. Dysfunctions in these complexes lead to diverse diseases. ...