Browsing by Subject "Eflornithine, oral bioavailability"

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    • Effects of oral administration of synthesized d-amides of eflornithine in the rat 

      Helena, Kevin J.; N'Da, David D.; Breytenbach, Jaco C.; Ashton, Michael; Johansson, Carl (Thieme, 2010)
      The purpose of this study was to synthesize a series of δ-amide derivatives of the antitrypanosomal drug eflornithine (2,5-diamino-2-(difluoromethyl)pentanoic acid hydrochloride, DMFO, CAS 70052-12-9), to determine their ...