Browsing by Subject "Common complex diseases"

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New mtDNA association model, MutPred variant load, suggests individuals with multiple mildly deleterious mtDNA variants are more likely to suffer from atherosclerosis

Piotrowska-Nowak, Agnieszka; Elson, Joanna L.; Sobczyk-Kopciol, Agnieszka; Piwonska, Aleksandra; Puch-Walczak, Aleksandra (Frontiers Media, 2019)

The etiology of common complex diseases is multifactorial, involving both genetic, and environmental factors. A role for mitochondrial dysfunction and mitochondrial DNA (mtDNA) variation has been suggested in the pathogenesis ...