Browsing by Subject "Caenorhabditis elegans"
Now showing items 1-6 of 6
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Anthelmintic potency of Rumex crispus L. extracts against Caenorhabditis elegans and non-targeted identification of the bioactive compounds
(Elsevier, 2021)Traditional healers and ethnoveterinary therapists use several medicinal plants, such as Rumex crispus L., to treat endoparasite infections. R. crispus has been established by researchers to be effective agasint a few ... -
Assessment of nematocidal activity of novel N-alkyl analogues of nitrofurantoin on Caenorhabditis elegans nematode model
(North-West University (South Africa), 2023)Caenorhabditis elegans is considered as a simple but important invertebrate model which provides a versatile platform of various experiments such as drug studies. The C. elegans is commonly used in anthelmintic drug studies ... -
Determining the ecotoxicity of nanodiamonds and quantum dots using the soil nematode Caenorhabditis elegans
(North-West University (South Africa), 2018)Engineered nanoparticles (ENP) are being used in many commercial products and applications, such as biological imaging, toothpaste and electronics. As the production, use and disposal of these products increase, environmental ... -
Evaluation of ROS production in OXPHOS knockout strains of C. elegans
(North-West University (South Africa), 2024)The oxidative phosphorylation (OXPHOS) system, comprising five complexes, regulates electron transport and adenosine triphosphate (ATP) synthesis in mitochondria. Dysfunctions in these complexes lead to diverse diseases. ... -
Evaluation of ROS production in OXPHOS knockout strains of C. elegans
(North-West University (South Africa), 2024-06)The oxidative phosphorylation (OXPHOS) system, comprising five complexes, regulates electron transport and adenosine triphosphate (ATP) synthesis in mitochondria. Dysfunctions in these complexes lead to diverse diseases. ... -
Oxygen consumption rate of Caenorhabditis elegans as a high-throughput endpoint of toxicity testing using the Seahorse XFe96 Extracellular Flux Analyze
(Nature Research, 2020)Caenorhabditis elegans presents functioning, biologically relevant phenotypes and is frequently used as a bioindicator of toxicity. However, most C. elegans in vivo effect-assessment methods are laborious and time consuming. ...