Browsing by Subject "Agomelatine"
Now showing items 1-3 of 3
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Behavioral, neuroendocrine and neurochemical studies on agomelatine in social isolation reared rats
(North-West University (South Africa) , Potchefstroom Campus, 2015)1. Introduction. There is currently a large body of evidence suggesting that stressful early life experiences, such as maternal separation and social isolation, may play a role in the development of major depressive disorder ... -
Evaluation of agomelatine treatment on neuroendocrine and behavioural markers in social isolation reared rats
(North-West University (South Africa) , Potchefstroom Campus, 2016)Anxiety disorders are extremely prevalent and co-morbid in psychiatric disorders with a complex neurobiology and aetiology. Current treatment options are not sufficiently effective and there is therefore a demand for new ... -
Studies into the anxiolytic actions of agomelatine in social isolation reared rats: role of corticosterone and sex
(Sage, 2018)Anxiety disorders are severely disabling, while current pharmacological treatments are complicated by delayed onset, low remission rates and side-effects. Sex is also noted to contribute towards illness severity and treatment ...