Browsing by Subject "Acetylcholinesterase"
Now showing items 1-4 of 4
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Design and synthesis of dual acting carbamate inhibitors of acetylcholinesterase and monoamine oxidase
(North-West University (South Africa) , Potchefstroom Campus, 2017)Alzheimer’s disease (AD), the most common neurodegenerative disorder, affects about 10% of the population over the age of 65 years. The disease is typified by symptoms such as memory loss and impairment in abilities including ... -
Evaluation of selected dye compounds as inhibitors of enzymes, relevant to neurological disorders
(North-West University (South-Africa), 2021)Neurological disorders such as Alzheimer’s disease, Parkinson’s disease and schizophrenia are disorders that affect a large part of the population, especially the elderly. The cause of these disorders is still not completely ... -
The interactions of azure B, a metabolite of methylene blue, with 2 acetylcholinesterase and butyrylcholinesterase
(Elsevier, 2014)Methylene blue(MB) is reported to possess diverse pharmacological actions and is attracting increasing attention for the treatment of neurodegenerative disorders such as Alzheimer's disease. Among the pharmacological actions ... -
Multifunctional enzyme inhibition for neuroprotection: a focus on MAO, NOS, and AChE inhibitors
(Elsevier, 2015)Neurodegenerative disorders are known to be multifactorial in nature and current research focus has moved from a ‘one-drug-one-target approach’ to that of drugs which are able to act at various relevant biological targets. ...