The influence of cardiac and vascular responses on basesline cardiovascular parameters in black african children
Date
2008Author
Fourie, Carla M.T.
Van Rooyen, Johannes M.
Huisman, Hugo W.
Malan, Nicolaas T.
Schutte, Rudolph
Malan, Leoné
Schutte, Aletta E.
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Show full item recordAbstract
Background: The prevalence of hypertension
among Black adults in South Africa is high.
Because cardiovascular reactivity can be used
to predict hypertension in later life, we
attempted to determine whether cardiac and
vascular responses to a task in Black South
African children influence their cardiovascular
parameters.
Design: This study was embedded in the
Transition and Health during Urbanization in
South Africa in Children study, which studied
the health status of children. During the study,
cardiovascular reactivity was determined with
a hand dynamometer in 670 Black African
children. Systolic blood pressure, diastolic
blood pressure, mean arterial pressure, heart
rate, stroke volume, cardiac output, total
peripheral resistance, and Windkessel compliance of the arterial system were obtained by
means of the Finapres (finger arterial pressure)
apparatus and the Fast Modelflow software
program. Anthropometric measurements were
performed according to standard methods.
Cardiac and vascular responders were classified with a regression-based approach.
Results: Cardiac responders had higher stroke
volume; a trend to higher cardiac output;
lower diastolic blood pressure; and a tendency
toward lower systolic blood pressure, heart
rate, and total peripheral resistance. Vascular
responders showed no significant changes in
cardiovascular parameters when responders
and nonresponders were compared.
Conclusions: Cardiac responders had higher
stroke volume and a trend toward higher
cardiac output, which may be an early
indication of hypertension
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- Faculty of Health Sciences [2377]