Malan, LeonéHamer, MarkVon Känel, RolandSmith, WayneSteyn, FaansMalan, Nicolaas2019-05-162019-05-162019Malan, L. et al. 2019. Stress and neurovascular coupling: a red flag? The SABPA study. 3rd Joint Meeting of the European-Society-for-Microcirculation (ESM) and the European-Vascular-Biology-Organization (EVBO), April 2019, Maastricht, Netherlands, Abstract 163. Journal of vascular research, 56 (Suppl 1):76. [https://doi.org/10.1159/000499516]1018-11721423-0135 (Online)http://hdl.handle.net/10394/32361https://www.karger.com/Article/Pdf/499516https://doi.org/10.1159/000499516Neuronal hyperactivity mediates communication between neurons and blood vessels (neurovascular coupling) and increases susceptibility for retinal ganglion cells functionality. Contrastingly, monoamine depletion and hypo-activity of cortisol reflected major depression, which may also disturb neurovascular coupling. Hence our objectives were to assess: 1) trajectories of two major stress hormones (norepinephrine and cortisol) over 3 yrs; and determine 2) associations between the retinal vasculature and stress hormone changes and responses during flicker-light-induced-provocation (FLIP)enPresentation