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Functional properties of metallothionein expression in mitochondrial NADH : ubiquinone oxidoreductase deficiency
(North-West University, 2004)
NADH:ubiquinone oxidoreductase (complex I) deficiency is one of the most frequently encountered causes of mitochondrial respiratory chain disorders. One of the major consequences of such a complex I deficiency is the ...
Perturbation of critical metabolic processes associated with 3-hydroxynorvaline induced teratogenesis
(North-West University, 2004)
Neural tube defects (NTD) are a group of folate-responsive congenital defects that
occur relatively frequently in humans. NTD display a multi-factorial aetiology, resulting from a complex interplay of genetic and environmental ...
Analysis of metallothionein expression levels in mitochondrial NADH:ubiquinone oxidoreductase deficiency
(North-West University, 2004)
Some well defined functions of crucial importance for cell physiology are carried out by mitochondria1 NADH:ubiquinone oxidoreductase (complex I). Deficiencies of this complex, which is one of the most frequently encountered ...