Now showing items 1-4 of 4
Metabolomics of hypertension in South Africans : the SABPA Study
(North-West University (South Africa), 2015)
There has been growing concern in recent years about the alarmingly high prevalence and severity of hypertension and other cardiovascular diseases in individuals from newly (or recently) westernised countries such as ...
Metallothionein involvement in mitochondrial function and disease : a metabolomics investigation
(North-West University, 2011)
One of the many recorded adaptive responses in respiratory chain complex I deficient cells is the over-expression of the small metal binding proteins, metallothioneins (MTs). The antioxidant properties of MTs putatively ...
Mitochondrial disorders in the South African context : a clinical and biochemical approach
(North-West University (South Africa), 2011)
In the past, patients with suspected mitochondrial disorders (MDs) were identified only phenotypically in South Africa. However, the specific population-related characteristics were unknown and not documented. Up to as ...
Urinary metabolomics investigation of Ndufs4 knockout mice
(North-West University (South Africa), 2020)
Mitochondrial diseases (MDs) are the most common inborn errors of metabolism, with an estimated prevalence of approximately 1 in 5 000 live births, and are mainly caused by deficiencies of complex I (CI) of the oxidative ...