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The effect of metallothionein overexpression on the transcription of selected genes involved in one-carbon metabolism and oxidative stress in NDUFS4-deficient mouse tissues
(North-West University (South Africa), 2020)
Respiratory complex I (CI) defects are the most common mitochondrial disease, for which treatment is limited. Additionally, there is a lack of understanding of the impact of a CI defect upon the gene expression regulation ...