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Sequencing and molecular characterization of variations in the glycine N–acyltransferase gene
Humans are continuously challenged by harmful endogenous and xenobiotic substances. Detoxification is the ability to neutralise and remove these substances from the body. Glycine N-acyltransferase, EC 18.104.22.168 (GLYAT) is ...
Identification and expression of proteases C. sonorensis and C. imicola important for African horsesickness virus replication
African horsesickness (AHS) is one of the most deadly diseases of horses, with a mortality rate of over 90% in horses that have not been exposed to any African horsesickness virus (AHSV) serotype previously (Howell, 1960; ...
A new perspective on the importance of glycine N–acyltransferase in the detoxification of benzoic acid
Despite being the first biochemical reaction to be discovered, the glycine conjugation pathway remains poorly characterised. It has generally been assumed that glycine conjugation serves to increase the water solubility ...
Investigating the importance of co-expressed rotavirus proteins in the development of a selection-free rotavirus reverse genetics system
Reverse genetics is an innovative molecular biology tool that enables the manipulation of viral genomes at the cDNA level in order to generate particular mutants or artificial viruses. The reverse genetics system for the ...