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Molecular analysis of the mitochondrial genome in South African patients with suspected mitochondrial disorders
(North-West University, 2003)
Human mitochondrial DNA (mtDNA) contains 37 genes, which encode 13 proteins (all subunits of the respiratory chain), 22 transfer ribonucleic acids (tRNA), and two ribosomal RNAs. The mtDNA mutation rate is approximately ...
Mitochondrial genome consensus sequence for the South African Khoi–San population
(North-West University, 2003)
Maternal inheritance and the absence of recombination have contributed to mitochondrial deoxyribonucleic acid (mtDNA) being utilised to study human evolution. This, together with an increased mutation rate in mtDNA, provides ...