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Diversity in the applications of the single cell gel electrophoresis (comet) assay
(North-West University, 2005)
The development of the single cell gel electrophoresis assay (Comet assay) as a
powerful method for measuring DNA strand breakage and repair, has lead to a broader understanding of the impact of certain internal and ...
Determining DNA damage and repair in human cells exposed to metabolites characteristic for tyrosinemia
(North-West University, 2005)
Hereditary Tyrosinemia (HTI) is an autosomal recessive disorder caused by a deficiency of fumarylacetoacetate hydrolase (FAH) but the mechanism by which the hepatic and renal symptoms of HTI arise is largely unknown. The ...
DNA damage and repair during the mammalian hormonal cycle
(North-West University, 2005)
The aim of this study was to determine the pattern of DNA damage and repair during the mammalian female hormonal cycle. This was done to determine whether the hormonal cycle must be taken into account when DNA damage and ...