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MtDNA landscape in South African paediatric patients clinically diagnosed with suspected mitochondrial disorders
(North-West University, 2004)
The relevance of haplogroups in mitochondrial disease was investigated in this study.
Twenty-seven paediatric patients with clinically suspected mitochondrial disorders from
diverse ethnic origins were investigated via ...
Analysis of metallothionein gene expression in oxidative stress related disorders
(North-West University, 2004)
Increased reactive oxygen species (ROS) have been reported to be at the centre of various diseases. Although several reports have implicated elevated levels of ROS in the
pathogenesis of diabetes mellitus, the early ...
Comparison of complete mitochondrial genome sequence between different ethnic groups from Southern Africa
(North-West University, 2004)
The human mitochondrial genome is a 16,569 base pair double-stranded deoxyribonucleic acid (DNA) molecule located in the mitochondrion. The mitochondria1 genome sequence is
conserved, maternally inherited and undergoes ...