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An untargeted LC-MS investigation of South African children with respiratory chain deficiencies
(2014)
Mitochondria are the main site of cellular adenosine triphosphate (ATP) generation which is achieved by a series of multi-subunit complexes and electron carriers which together create the oxidative hosphorylation system ...
Metabolic variation in cultured cells treated with differentially functionalised gold nanoparticles (GNPs)
(North-West University (South Africa), Potchefstroom Campus, 2017)
Gold nanoparticles (GNPs) and differentially functionalised or ligand exchanged GNPs (Lig-GNPs) present promising advantages in a variety of fields. Surface functionalisation of GNPs with ligands is believed to improve the ...
Improving a biosignature for respiratory chain deficiencies in a South African cohort
(North-West University (South Africa) , Potchefstroom Campus, 2016)
Mitochondria are the cell’s main energy producing site, found in the cytoplasm of nearly all eukaryotic cells. These organelles generate cellular energy in the form of adenosine triphosphate (ATP), mostly by means of the ...