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Now showing items 31-40 of 70
Characterisation of the ?2A-adrenoceptor antagonism by mirtazapine and its modifying effects on receptor signalling
(North-West University, 2004)
Mirtazapine is an atypical antidepressant employed clinically for the treatment of major depression. As a multipotent antagonist it acts at α2a-adrenergic receptors (α2a -ARs). serotonin type-2A receptors (5-HT2a-Rs) and ...
An analysis of the usage of antibiotics in the private health care sector : a managed health care approach
(North-West University, 2004)
The most frequent intervention performed by physicians is the writing of a prescription. Modern medicine has been remarkably effective in managing diseases. Medicines play a fundamental role in the effectiveness, efficiency ...
Assessment of the tableting properties of chitosan through wet granulation and direct compression formulations
(North-West University, 2004)
Chitosan is a natural polysaccharide that is obtained by the partial deacetylation of chitin, the second most abundant natural polymer. Chitosan is currently extensively
utilised in various pharmaceutical and non-pharmaceutical ...
Antihistamines as neuroprotective agents
(North-West University, 2004)
Biomolecules are continuously exposed to potentially harmful oxidative stress as a consequence of free radical formation. Increased free radical generation has been associated with aging as well as neurodegenerative ...
Aspects of drug usage in a private primary health care setting : a pharmacoeconomic approach
(North-West University, 2004)
In South Africa, significant changes in health care have taken place since the first democratic elections in 1994. The change had lead to a position of integrated service delivery with specific reference to primary health ...
Antimalarial compounds from Crinum Bulbispermum
(North-West University, 2004)
Malaria is caused by protozoan parasites of the genus Plasmodium, of which Plasmodium falciparum is the most widespread and dangerous. Around 800 000 children under the age of five die from malaria every year. An increase ...
Beliefs and practices related to label reading and its implications for functional foods in South Africa
(North-West University, 2004)
Motivation - There is international agreement and recognition that the health status of the worlds' population is a cause for concern and that one of the key risk factors for many of the diseases that are increasing at an ...
Job insecurity and wellness of workers in a local government organisation
(North-West University, 2004)
The industrialised world of today are characterised by transformation and concepts such as downsizing, rightsizing and restructuring have become a reality. South Africa is not excluded from this worldwide phenomenon and ...
Usage patterns and cost analysis of angiotensin-converting enzyme (ACE) inhibitors using a medical aid claims database
(North-West University, 2004)
ACE inhibitors have been widely used in the treatment of certain diseases of the
cardiovascular system, the major use being hypertension, since all ACE inhibitors are prescribed for its treatment. ACE inhibitors is also ...
A comparative study between two lamellar gel phase systems and Emzaloids as delivery vehicles for the transdermal delivery of 5-fluorouracil and idoxuridine
(North-West University, 2004)
The distinctive architecture of the stratum corneum with its unique nature of an
interstitial lipoidal environment plays the major role in regulating the barrier function of the skin. The major problem with the transdermal ...