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Now showing items 31-40 of 56
Formulation, in vitro release and transdermal diffusion of acyclovir and ketoconazole for skin conditions in HIV/AIDS patients
(North-West University, 2009)
The aim of this in vitro study was to investigate the efficacy of the novel Pheroid™ technology system in a semi-solid dosage form, for the topical delivery of acyclovir (5% w/w), an anti-viral agent and ketoconazole (2% ...
Formulation and evaluation of different transdermal delivery systems with flurbiprofen as marker
(North-West University, 2012)
The aim of this study was to investigate the effect of different penetration enhancers containing essential fatty acids (EFAs) on the transdermal delivery of flurbiprofen. Flurbiprofen was used as a marker / model compound. ...
The transdermal delivery of arginine vasopressin with pheroid technology
(North-West University, 2007)
The aim of this study was to investigate in vitro transdermal diffusion of a small peptide namely arginine vasopressin (AVP) with the aid of the novel PheroidTM drug delivery system. Generally, peptides seem unfit for ...
Formulation, characterisation and topical application of oil powders from whey protein stabilised emulsions
(2014)
The available literature indicates that to date, few research has been performed on oil powders for topical delivery. The aim of this project was to investigate the release characteristics of oil powder formulations, as ...
Formulation, in vitro release and transdermal diffusion of diclofenac salts by implementation of the delivery gap principle
(2013)
Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used in the treatment of inflammation and pain (Escribano et al., 2003:203). Diclofenac, a classical NSAID, is considerably more effective as an analgesic, antipyretic ...
The synthesis and transdermal delivery of stavudine derivatives
(North-West University, 2006)
The skin is an amazingly flexible and relatively impermeable barrier that provides
protective, perceptive and communication functions to the human body. The interest in
transdermal drug delivery may be attributed to the ...
Pheroid technology for the topical delivery of depigmenting agents transforming growth factor–ß1 and tumor necrosis factor–a
(North-West University, 2010)
Pigmentation disorders occur in multiple conditions (Hakozaki et al., 2006:105). Although many modalities of treatments are available, none are completely satisfactory (Briganti et al., 2003:101). Two cytokines normally ...
Formulation of 5–Fluorouracil for transdermal delivery
(North-West University, 2010)
Non–melanoma skin cancer (NMSC) is the most common human malignancy and it is estimated that over 1.3 million cases are diagnosed each year in the United States (Neville et al., 2007:462). There are three main types of ...
Formulation and topical delivery of liposomes and proliposomes containing clofazimine
(North-West University (South Africa) , Potchefstroom Campus, 2016)
The continual market increase in the transdermal and topical delivery of drugs makes cutaneous drug delivery exploration all the more attractive for scientists (Larraῆeta et al., 2016:62). The key in the delivery of drugs ...
Characterisation, toxicology and clinical effects of crocodile oil in skin products
(North-West University, 2012)
Natural oils are regularly used in cosmetics and as treatment for numeral skin conditions (Nielsen, 2006:575). The natural products industry is a multibillion dollar industry and has grown tremendously over the past few ...