Search
Now showing items 21-30 of 54
The synthesis and evaluation of 8–benzyloxycaffeine analogues as inhibitors of monoamine oxidase B
(North-West University, 2009)
Monoamine oxidase, especially monoamine oxidase 8 (MAO-B), plays a major role in the therapy of Parkinson's disease (PO). MAO-8 is the main enzyme responsible for the catabolism of dopamine in the substantia nigra of the ...
Effect of a combined rugby conditioning and plyometric training program on selected physical and anthropometric components of university–level rugby players
(North-West University, 2009)
Plyometrics is a specialized, high-intensity training technique for the improvement of power and performances among athletes primarily participating in dynamic, explosive type of team sports such as rugby league and soccer. ...
The impact of PheroidTM technology on the bioavailability and efficacy of anti-tuberculosis drugs in an animal model
(North-West University, 2009)
Tuberculosis (TB) is a worldwide pandemic with vast challenges in the fight against the
disease. Challenges include the long and tedious treatment regimens and chemotherapy with
adverse side effects. One approach in ...
The relationship between baroreflex sensitivity and cardiovascular function in Africans and Caucasians from South Africa : the SAfrEIC study
(North-West University, 2009)
In the past four decades Africans from Sub-Saharan Africa has become more westernised due to increasing urbanisation. Along with this came changes in lifestyle and diet, which consequently led to the increased prevalence ...
Formulation, in vitro release and transdermal diffusion of salicylic acid and topical niacinamide
(North-West University, 2009)
Acne affects as many as 80% of young adults and adolescents all over the world. This detrimental condition can be classified into four stages: (a) open comedo (blackhead), (b) closed comedo (whitehead), (c) papule and (d) ...
Formulation, in vitro release and transdermal diffusion of vitamin B3 for treatment of acne
(North-West University, 2009)
Acne is an extremely common condition, affecting almost 80% of adolescents and young adults. It is an inflammatory disease, characterised by comedones, papules, pustules and sometimes cysts. Factors causing acne include ...
Formulation, in-vitro release and transdermal diffusion of alpha-lipoic acid
(North-West University, 2009)
Acne is a common disease characterised by follicular hyperkeratinisation, bacterial hipercolonisation as well as immune reactions and inflammation. In acne, reactive oxygen species (ROS) may be released from the damaged ...
Formulation, in vitro release and transdermal diffusion of isoniazide and rifampicin for dermal tuberculosis
(North-West University, 2009)
Extra pulmonary tuberculosis makes up 10% of all tuberculosis cases and cutaneous tuberculosis (CTB) only a fraction of this 10%. CTB is caused by mainly Mycobacterium tuberculosis and can lead to scarring and deformities. ...
Polycyclic propargylamines as multi-functional neuro-protective agents
(North-West University, 2009)
The pathology of neurodegenerative disorders, such as Parkinson's disease (PD) and
Alzheimer's disease (AD), is caused by the abnormal loss of neuronal cells in certain areas of the brain. It consequently causes an imbalance ...
Positive practice environments in critical care units : a grounded theory
(North-West University, 2009)
INTRODUCTION AND AIM: The current shortage of nurses is a concern shared by the healthcare industry globally. Whilst the reasons for these shortages are varied and complex, a key factor among them seem to involve an unhealthy ...