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Now showing items 21-30 of 56
Formulation, in vitro release and transdermal diffusion of azelaic acid with topical niacinamide
(North-West University, 2010)
Acne is a common skin disease that affects the follicular unit of the skin. Inflammatory- and noninflammatory forms of acne exist. The most affected areas on the body include the face, upper part of the chest and the back. ...
Formulation, in vitro release and transdermal diffusion of isoniazide and rifampicin for dermal tuberculosis
(North-West University, 2009)
Extra pulmonary tuberculosis makes up 10% of all tuberculosis cases and cutaneous tuberculosis (CTB) only a fraction of this 10%. CTB is caused by mainly Mycobacterium tuberculosis and can lead to scarring and deformities. ...
Formulation, in vitro release and transdermal diffusion of anti-inflammatory gel preparations containing diclofenac salts
(North-West University, 2010)
Most individuals are influenced by pain at some stage in their lives. It can either be of acute or chronic nature. An acute pain condition initiates and is treated within a time span of 12 weeks. Chronic pain can, however, ...
Pheroid technology for the transdermal delivery of lidocaine and prilocaine
(North-West University, 2008)
Local anaesthetics have been implemented extensively in the case of a variety of painful
superficial procedures, venipuncture, skin graft harvesting, anal or genital pruritus, poison ivy rashes, postherpetic neuralgia ...
PheroidTM technology for the topical application of selected cosmeceutical actives
(North-West University, 2008)
Aging can be described as an extremely complex occurrence from which no organism can be excluded. Intrinsic and extrinsic aging make out the two components of skin aging and they differ on the macromolecular level while ...
Topical delivery of artemether, encapsulated in niosome and proniosome carriers
(North-West University (South Africa) , Potchefstroom Campus, 2016)
Artemisia annua is a Chinese herb discovered by Chinese scientists in 1971. Artemisinin
was extracted from this herb and used as a Chinese medicine named Qinghaosu.
Artemether (ARM) is a derivative from the artemisinin ...
Percutaneous delivery of thalidomide and its N-alkyl analogues for treatment of rheumatoid arthritis
(Potchefstroom University for Christian Higher Education, 1998)
Rheumatoid arthritis (RA) is a chronic inflammatory joint disease associated with high levels of tumour necrosis factor-alpha (TNF-a) in synovial fluid and synovial tissue (Saxne et al., 1989). Thalidomide is a proven ...
Comparative study of the topical delivery of selected female hormones
(North-West University (South-Africa), 2020)
Intrinsic skin ageing is predominantly caused by a decrease in female hormones as menopause approaches. It is suggested that topical application of female hormones may treat these ageing symptoms. Unfortunately, the ...
Formulation of an emulgel for topical delivery of roxithromycin
(North-West University (South-Africa), 2020)
The aim of this study was to establish whether liposomal or niosomal vesicle systems containing roxithromycin could be developed further into semi-solid formulations (emulgels) for topical delivery of the active pharmaceutical ...
In vitro efficacy of cations incorporated in Absorbatox® for wound healing
(North-West University (South-Africa), 2020)
Wound healing can be described as a cascade of cells activated to restore tissue integrity, in order to regain the body’s natural function. Wound care plays a pivotal role in achieving therapeutic outcomes in wounds to ...