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    Synthesis and biological evaluation of novel artemisone derivatives 

    Mabilika, Richard James (North-West University (South Africa) , Potchefstroom Campus, 2015)
    Despite intensive international efforts to eradicate malaria, the disease, continues to inflict an enormous toll on human lives, especially in Africa. An estimated 198 million malaria cases and 584, 000 deaths were reported ...
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    Triazole-linked 1,4-naphthoquinone derivatives : synthesis and antiplasmodial activity 

    Erasmus, Chané (North-West University (South-Africa). Potchefstroom Campus, 2019)
    Malaria is a protozoan disease transmitted to humans through female Anopheles mosquitoes. The malaria parasite thrives in tropical areas, thus people there are at higher risk, especially in third-world countries like ...
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    Development and evaluation of an oral fixed–dose triple combination dosage form for artesunate, dapsone and proguanil 

    Van der Merwe, Adriana Johanna (North-West University, 2011)
    Malaria is a life–threatening disease caused by Plasmodium spp and causes over one million deaths annually. The complex life cycle of the malaria parasite offers several points of attack for the antimalarial drugs. The ...
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    In vitro antimalarial efficacy enhancement of selected antibiotics with PheroidTM technology 

    Van Niekerk, Elizabeth Catharina (North-West University, 2010)
    The Plasmodium falciparum parasite, carried by Anopheles mosquitoes, is currently a global problem due to the rising incidence of resistance of the parasite to available antimalaria drugs. Resistance and difficult treatment ...
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    Dihydroartemisinin esters as prodrugs against resistant P. falciparum strains 

    Krebs, Johann Hendrik (North-West University, 2011)
    Malaria is caused by the Plasmodium sp. parasite that infects the red blood cells. Of the four types of malaria, the most serious type is transmitted by Plasmodium falciparum species. It can be life threatening. The other ...
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    Artemisinin–quinoline hybrids : design, synthesis and antimalarial activity 

    Vlok, Martha Carolina (North-West University, 2013)
    Introduction - Malaria is a major global health problem, with more than 500 million reported cases and at least 1 million deaths each year. The main problem with malaria control is the emerging drug resistance. Plasmodium ...
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    Development and evaluation of a solid oral dosage form for an artesunate and mefloquine drug combination 

    Van der Watt, Abel Hermanus (2014)
    Malaria affects about forty percent of the world’s population. Annually more than 1.5 million fatalities due to malaria occur and parasite resistance to existing antimalarial drugs such as mefloquine has already reached ...
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    The effect of Pheroid® technology on the bioavailability of artemisone in primates 

    Grobler, Lizette (2014)
    Malaria is one the world’s most devastating diseases. Several classes of drugs are used to treat malaria. Artemisinin combination therapy is the first line treatment of uncomplicated malaria. The artemisinin derivative, ...
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    Synthesis and antimalarial activity screening of artemisinin-acridine hybrids 

    Joubert, Juan Paul (2013)
    Malaria endemic areas not only pose a public health threat, but affects 3.3 billion people worldwide. In 2011, estimated malaria related deaths amounted to 660 000 out of 219 million reported cases, with 81% of these and ...
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    Formulation, characterisation and in vivo efficacy of dapsone and proguanil in trimethylated chitosan microparticles 

    Van Heerden, Jacobus (2014)
    Malaria is an infectious disease caused by various forms of the Plasmodium parasite. It is responsible for thousands of deaths yearly with 90 % of those deaths being in sub-Saharan Africa, thus making it a disease of global ...
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    AuthorBritz, Chantal (1)Cheng, Ndong Ignatius (1)Cilliers, Lauren (1)De Lange, Christo (1)Erasmus, Chané (1)Gibhard, Liezl (1)Grobler, Lizette (1)Harmse, Rozanne (1)Hattingh, S. (1)Joubert, Juan Paul (1)... View MoreSubject
    Malaria (26)
    Plasmodium falciparum (7)Artemisinin (4)Amodiakien (3)Artemisinin-based combination therapy (3)Artesunate (3)Hybrids (3)Mefloquine (3)Amodiaquine (2)Artemether (2)... View MoreDate Issued2010 (5)2014 (5)2019 (4)2013 (3)2011 (2)2015 (2)2017 (2)2012 (1)2016 (1)2018 (1)Has File(s)Yes (26)

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