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An investigation into the potential neurobiological constructs and long-term biobehavioural effects of perinatal combined antiretroviral therapy (cART)-exposure in the deer mouse
(North-West University (South-Africa), 2022)
South Africa has one of the largest combination antiretroviral treatment (cART1) programs in the world with an estimated 7.52 million individuals that were living with human immunodeficiency virus (HIV2) by the end of 2018. ...
Exercise-induced lipid mediator inflammatory signalling in male recreational runners versus untrained males considering potential modulating factors
(North-West University (South-Africa), 2019)
Background: Resistance exercise can cause inflammation and it is known that inflammation is closely related to oxidative stress. Oxidative stress can be defined as an imbalance between free radicals and anti-oxidative ...
Vascular function, oxidative stress and inflammation in South Africans with an active-and inactive lifestyle: the SABPA study
(North-West University (South-Africa), 2019)
Motivation - Cardiovascular disease was responsible for 17.5 million deaths in 2014, which made it the main cause of mortality among non-communicable diseases. Statistics from low- and middleincome countries demonstrated ...
The role of endothelin-1 in cardiometabolic and vascular function in a bi-ethnic population : the SABPA study
(North-West University (South Africa) , Potchefstroom Campus, 2017)
Motivation
The black population in South Africa has a high prevalence of hypertension and atherosclerosis. Endothelin-1 (ET-1), a potent vasoconstrictor peptide, has been implicated as an important biomarker in the ...