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Artemisinin–quinoline hybrids : design, synthesis and antimalarial activity
(North-West University, 2013)
Introduction - Malaria is a major global health problem, with more than 500 million reported cases and at least 1 million deaths each year. The main problem with malaria control is the emerging drug resistance. Plasmodium ...
Synthesis and antimalarial activity screening of artemisinin-acridine hybrids
(2013)
Malaria endemic areas not only pose a public health threat, but affects 3.3 billion people
worldwide. In 2011, estimated malaria related deaths amounted to 660 000 out of 219 million reported cases, with 81% of these and ...