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Percutaneous absorption of cyclizine and its alkyl analogues
(North-West University, 2003)
Percutaneous delivery of drugs promises many advantages over oral or intravenous
administration, such as a better control of blood levels, a reduced incidence of systemic
toxicity, an absence of hepatic first-pass ...
Isolation and characterisation of antimicrobial compounds from Antizoma angustifolia
(North-West University, 2004)
Infectious diseases are responsible for more than 17 million deaths per year worldwide, most of which are associated with bacterial infections. The increase in antibiotic resistance is thought to be a contributing factor ...
Red yeast epoxide hydrolases : growth, activity and selectivity
(North-West University, 2007)
Enantiopure epoxides are versatile compounds in the production of single enantiomer drugs, and are of high value as building blocks and intermediates in the preparation of more complex single enantiomer pharmaceuticals and ...
The dissolution analysis of sulfadoxine/pyrimethamine combination tablets
(North-West University, 2007)
Disease is as old as life itself and the treatment thereof ancient too. A disease that still claims over a million lives annually and is considered a health problem in approximately 90 countries is malaria, even though it ...
Trifluoromethyl-substituted quinoline and tetrazole derivatives :design, synthesis, antimalarial activity and cytotoxicity
(North-West University, 2008)
Malaria is a complex parasitic disease caused by the Plasmodium falciparum. It has been found to be responsible for the death of many people particularly in under-developed and developing countries. For many years chloroquine ...
Design and characterization of asymmetrical porous nickel membranes
(North-West University, 2006)
As an alternative to organic membranes, ceramic membranes are suitable for the chemical industry due to their intrinsic thermal, chemical and mechanical stability. The centrifugal dispositioning technique has the advantage ...
Direct crystallisation of hydroxysodalite and MFI membranes on α-alumina supports
(North-West University, 2005)
Hydroxysodalite and MFI are zeolites that consist of crystalline (tecto)aluminosilicates and silicates with specific aperture sizes. Zeolite membranes are suited for any process requiring separation on a molecular level ...
Synthesis and transdermal permeation of lamivudine derivatives
(North-West University, 2009)
The skin is the organ of the body that comes in contact with the outer environment. This means
that it has certain functions like protecting the body from excessive water loss and inhibiting the
entry of potentially ...
Time-dependent growth of ceramic supported NaA membranes : a morphological and permeation based study
(North-West University, 2006)
Based on its ideal aperture size (4.1 A) and hydrophilic framework, the NaA membrane possesses significant potential in the separation of many industrially important gaseous and liquid mixtures. In the local South African ...
Optimisation of a stereoconvergent process catalysed by whole yeast cells
(North-West University, 2008)
Stereochemistry, defined as being the study of the spatial behaviour of atoms in molecules and complexes, has become increasingly important in the pharmaceutical sector. In particular, the existence and pharmacological ...