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The role of diet in cardiovascular disease in black South Africans : both sides of the story
(North-West University, 2013)
Background: Cardiovascular disease (CVD) is becoming one of the leading causes of death in middle and low income countries, with ischaemic heart disease specifically being predicted to be the 4th and 5th causes respectively. ...
Using benefit levers to develop an operational plan for spread of best practices in health systems
(North-West University, 2013)
This study addressed the use of benefit levers to develop a guide for an operational plan for spread of best practices in the health system of South Africa.
Using the best evidence to inform practice is the cornerstone ...
Syntheses of sulfanylphthalimide and xanthine analogues and their evaluation as inhibitors of monoamine oxidase and as antagonists of adenosine receptors
(North-West University, 2013)
Currently L-DOPA is the drug most commonly used for the treatment of Parkinson’s disease (PD). However, the long-term use of L-DOPA is associated with the development of motor fluctuations and dyskinesias. Treatment mainly ...
Syntheses of chalcones and 2–aminopyrimidines and their evaluation as monoamine oxidase inhibitors and as adenosine receptor antagonists
(North-West University, 2013)
Background and rationale - Parkinson’s disease is a neurodegenerative disorder characterised by reduced levels of
dopamine in the brain. The cause of Parkinson's disease is still unknown; however several theories pertaining ...
Syntheses of 8–(phenoxymethyl)caffeine analogues and their evaluation as inhibitors of monoamine oxidase and as antagonists of the adenosine A2A receptor
(North-West University, 2013)
Background and rationale: Parkinson’s disease (PD) is a progressive, degenerative disorder of the central nervous system and is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta. The ...
Body composition profiles of underweight and obese grade one learners in the North West Province of South Africa : NW–CHILD study
(North-West University, 2013)
Body composition profiles including stunting, wasting and underweight, overweight and obesity, can all affect the health, motor development and academic achievements of children. South Africa (SA), a developing, middle-income ...
The dynamics of psycho–social well–being in Afri Twin schools
(North-West University, 2013)
This study, presented in the format of three articles, contributed to the measuring of psycho-social well-being in Afri Twin schools. The literature points to a serious lack of studies measuring the psychosocial well-being ...
The relevance of specific c–reactive protein genetic variants towards cardiovascular disease risk in a black South African population undergoing an epidemiological transition
(North-West University, 2013)
Introduction: In Africa, it is estimated that cardiovascular disease (CVD) will affect approximately 1.3 million people per annum over the following 20 years. C-reactive protein (CRP) is a predictor of CVD risk and certain ...
Exploring community–based interventions for mentally ill patients to improve quality of care
(North-West University, 2013)
Mentally ill patients need to be treated with dignity and their basic human rights must be respected. Community-based interventions are commonly used in many areas after deinstitutionalisation of mentally ill patients. ...
Permeation of excised intestinal tissue by insulin released from Eudragit® L100/Trimethyl chitosan chloride microspheres
(North-West University, 2013)
The purpose of this research project was to develop and characterise matrix type microspheres prepared from Eudragit® L100, containing insulin as model peptide drug as well as an absorption enhancer, N-trimethyl chitosan ...