Now showing items 1-3 of 3
The effect of early–life exposure of rats to venlafaxine on behaviour and neurological markers of antidepressant action in adulthood
Major depression is a serious mood disorder affecting more than 120 million people worldwide, irrespective of their race or socio-economic status. This psychiatric disorder is predicted to become the second leading cause ...
Evaluating the antidepressant-like properties of Sceletium tortuosum, alone and as adjunctive treatment
(North-West University (South-Africa), 2020)
BACKGROUND: Millions of people worldwide suffer from major depressive disorder (MDD) which can cause physical and emotional suffering for patients and their loved-ones. Unfortunately current treatment fails in approximately ...
The modulatory effects of sildenafil and the cholinergic system on antidepressant action in a rat model of depression
(North-West University, 2006)
Sildenafil, a selective phosphodiesterase type 5 (PDE5) inhibitor, is registered for the treatment of male erectile dysfunction (Viagra®) and pulmonary hypertension (Revatio®) in the United States. PDE5 is found in the ...