Now showing items 1-2 of 2
An investigation into the antidepressant–like profile of pioglitazone in a genetic rat model of depression
(North-West University, 2011)
Major depression is a highly prevalent mood disorder with chronic debilitating effects. Additional to a rising rate in incidence, depression is highly co–morbid with other psychiatric disorders, but also chronic cardiometabolic ...
Development and validation of an animal model of treatment resistant depression
(North-West University (South Africa) , Potchefstroom Campus, 2017)
The current investigation focused on the development and validation of an animal model of treatment resistant depression (TRD). In addition, an in-depth review of biomarkers of depression was included which aimed to identify ...