Browsing Health Sciences by Subject "Pheroid"
Now showing items 1-8 of 8
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Formulation, in vitro release and transdermal diffusion of isoniazide and rifampicin for dermal tuberculosis
(North-West University, 2009)Extra pulmonary tuberculosis makes up 10% of all tuberculosis cases and cutaneous tuberculosis (CTB) only a fraction of this 10%. CTB is caused by mainly Mycobacterium tuberculosis and can lead to scarring and deformities. ... -
Pheroid technology for the topical delivery of depigmenting agents transforming growth factor–ß1 and tumor necrosis factor–a
(North-West University, 2010)Pigmentation disorders occur in multiple conditions (Hakozaki et al., 2006:105). Although many modalities of treatments are available, none are completely satisfactory (Briganti et al., 2003:101). Two cytokines normally ... -
Pheroid technology for the transdermal delivery of lidocaine and prilocaine
(North-West University, 2008)Local anaesthetics have been implemented extensively in the case of a variety of painful superficial procedures, venipuncture, skin graft harvesting, anal or genital pruritus, poison ivy rashes, postherpetic neuralgia ... -
Pre-clinical evaluation of the possible enhancement of the efficacy of antiretroviral drugs by pheroid technology
(North-West University, 2007)HIV/AIDS is the most threatening and challenging infectious diseases of our time, with the highest increase of newly infected cases reported. This infectious disease was discovered in the early eighties under homosexual ... -
Preparation and characterisation of pheroid vesicles
(North-West University, 2006)Pheroid is a patented system comprising of a unique submicron emulsion type formulation. Pheroid vesicles consist mainly of plant and essential fatty acids and can entrap, transport and deliver pharmacologically active ... -
Radio-labelling as a tool to investigate the absorption and bio-distribution of selected antimalarial drugs
(2014)Previous studies have shown that the formulation of an active pharmaceutical ingredient (API) entrapped in the Pheroid® (Pheroid for simplification) delivery system enhances absorption of the API, suppresses its metabolism, ... -
The transdermal delivery of arginine vasopressin with pheroid technology
(North-West University, 2007)The aim of this study was to investigate in vitro transdermal diffusion of a small peptide namely arginine vasopressin (AVP) with the aid of the novel PheroidTM drug delivery system. Generally, peptides seem unfit for ... -
Transdermal delivery of isoniazid and rifampicin by pheroid technology
(North-West University, 2007)The aim of this in vitro study was to investigate the feasibility of the transdermal delivery of isoniazid (INH) and rifampicin (RMP) by means of the novel PheroidTM technology system. The application of the latter is ...