Browsing Health Sciences by Subject "Insulin"
Now showing items 1-8 of 8
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Cardiovascular dysfunction in black South Africans: an investigation from various perspectives
(North-West University, 2010)Motivation: The prevalence of cardiovascular dysfunction, especially hypertension, in Africans has increased dramatically over the past few decades. Despite considerable in- depth studies, cardiovascular diseases remain ... -
Development of a double phase dosage form for enhanced peptide drug delivery
(2015)Parenteral administration remains the most utilised route of administration for therapeutic peptides due to low intestinal epithelial permeability. However, the most convenient and popular route of drug administration ... -
Dietary calcium intake and obesity in adult women : the POWIRS study
(North-West University, 2004)Background: The role of dietary calcium in weight management is gaining support in the nutrition research community. It has been hypothesized that high calcium diets protect against fat gain by creating a balance of lipolysis ... -
The effect of the glycaemic index of a pre-exercise meal on the glycaemic and insulin responses during acute exercise
(North-West University (South-Africa), 1999)Introduction : The objectives of this study were to examine the role of the glycaemic index of a pre-exercise meal, ingested 1 hour before an acute exercise test (15 -20 min), on the metabolic profile of elite athletes ... -
Gastrointestinal region specific insulin absorption enhancement by Aloe vera leaf materials
(North-West University (South Africa) , Potchefstroom Campus, 2015)The oral administration route is still the most popular and preferred route for drug administration, but is, however, not suitable for protein and peptide drugs such as insulin, due to their poor bioavailability when ... -
Nasal delivery of insulin with Pheroid technology
(North-West University, 2006)Approximately 350 million people worldwide suffer from diabetes mellitus (DM) and this number increases yearly. Since the discovery and clinical application of insulin in 1921, subcutaneous injections have been the standard ... -
Peroral and nasal delivery of insulin with PheroidTM technology
(North-West University, 2009)Since its initial discovery in 1922 by Banting and Best, the formulation of an oral insulin delivery system has ever been so troublesome. Unfortunately, insulin is indispensable in the treatment of diabetes mellitus, which ... -
Preparation and evaluation of multiple-unit solid oral dosage forms containing chemical permeation enhancing agents
(2014)The most popular and convenient route of drug administration remains the oral route, however, protein and peptide drugs such as insulin have poor membrane permeability and stability in the gastrointestinal tract. Absorption ...