Browsing Health Sciences by Subject "Ex vivo"
Now showing items 1-7 of 7
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The effects of selected health supplements on drug intestinal epithelial permeation
(North-West University (South-Africa), 2019)With the growing popularity of health supplement usage to support and maintain a healthy body there is an increasing concern for possible drug-drug and drug-supplement interactions because health supplements are not subjected ... -
Evaluation of the effect of colloidal systems on biodistribution of selected prostate cancer radiopharmaceuticals
(North-West University (South-Africa), 2019)It has been reported that microemulsion (ME) delivery systems provide an opportunity to enhance the bioavailability and efficacy of a therapeutic agent whilst minimising side effects. The prostate-specific membrane antigen ... -
Evaluation of the effects of selected disintegrants on drug membrane permeation
(North-West University (South Africa) , Potchefstroom Campus, 2016)Virtually all solid dosage forms contain a disintegrating agent to help facilitate breakup, dissolution and absorption. Traditionally, excipients were thought to be pharmacologically inert, but recently, an increasing ... -
An ex vivo investigation of the potential drug permeation enhancing effects of selected pepper extracts
(North-West University (South-Africa), 2019)Although the oral route is the most preferred and convenient route of drug administration when considering the patient, certain drugs (e.g. protein and peptide drugs) are mostly administrated by means of injections. This ... -
Extemporaneously prepared astaxanthin capsules for improved systemic delivery
(North-West University (South-Africa), 2020)Extemporaneous compounding of supplements or drugs has been practised since the beginning of pharmaceutical disease treatment approaches. In recent years extemporaneous compounding methods have been used for the formulation ... -
Investigations on the respiratory effects of ozone in the rodent
(North-West University, 2010)Ozone, being an unstable molecule, is believed to be one of the strongest oxidant agents known to man. Rapid growth in the application of ozone — both as disinfectant and as form of alternative medicine — led to questions ... -
Pharmacokinetic interactions: the effect of herbal extracts and supplements on drug permeation
(North-West University, 2018)The surge in popularity to treat illnesses with a more holistic approach is causing growing concern due to the increasing occurrence of adverse reactions, which are the result of interactions due to the concomitant use of ...