Browsing Health Sciences by Subject "Clofazimine"
Now showing items 1-5 of 5
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Development of a topical self-emulsifying drug delivery system for optimised delivery
(North-West University (South-Africa), 2020)In order to achieve successful receptor binding affinity at complex pharmacological targets the majority of drugs are of a lipophilic nature. However, optimisation of drug delivery systems for lipophilic drugs presents ... -
Formulation and topical delivery of liposomes and proliposomes containing clofazimine
(North-West University (South Africa) , Potchefstroom Campus, 2016)The continual market increase in the transdermal and topical delivery of drugs makes cutaneous drug delivery exploration all the more attractive for scientists (Larraῆeta et al., 2016:62). The key in the delivery of drugs ... -
Natural oil nano-emulsion dispersions for the topical delivery of clofazimine, artemisone and decoquinate
(North-West University, Potchefstroom Campus, 2018)Tuberculosis (TB), which is caused by Mycobacterium tuberculosis (Mtb) (Godreuil et al., 2007:1), manifests as an extra-pulmonary disease in 3.7 to 8.4% of cases, whereas cutaneous tuberculosis (CTB), which is uncommon, ... -
Topical delivery of clofazimine from an avocado oil nano-emulsion
(North-West University (South Africa) , Potchefstroom Campus, 2016)The skin is the largest organ of the human body (Finch, 2003:29). The outermost layer of the skin, the stratum corneum, offers a protective barrier that prevents foreign substances from penetrating into the body through ... -
Topical delivery of clofazimine, artemisone and decoquinate utilizing vesicles as carrier system
(North-West University, 2018)Artemisone, clofazimine and decoquinate are part of the MALTBRedox MRC South African University Flagship Projects, which focus on oxidant-redox drug combinations for the treatment of tuberculosis and a few other diseases. ...