Browsing Health Sciences by Subject "Aloe vera"
Now showing items 1-10 of 11
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Combining chemical permeation enhancers to obtain synergistic effects
(2014)The oral route of administration remains the preferred route of administrating drugs due to patient acceptance and compliance. Therapeutic proteins are currently mainly administered by means of the parenteral route because ... -
Combining selected medicinal plant extracts to improve wound healing of the skin
(North-West University (South-Africa), 2021)Throughout history plant-based medicines have been used for the treatment and management of wounds and some of these natural remedies are still very popular. Aloe vera gel is a well-known medicinal plant widely used in ... -
Development of a mini-tablet-in-capsule dosage form for macromolecular drug delivery
(North-West University (South-Africa), 2020)Oral delivery of protein and peptide drugs faces immense challenges, partially due to the inherent unfavourable characteristics of the molecules and partially due to the unfavourable gastrointestinal environment. These ... -
Drug absorption enhancement capacities and mechanisms of action of Aloe vera gel materials
(North-West University (South Africa), Potchefstroom Campus, 2018)Oral drug delivery is one of the most preferred and user friendly routes of drug administration. Macromolecular drugs (such as peptides and proteins) generally have a poor bioavailability when administered orally. Absorption ... -
Effects of selected plant materials on in vitro wound healing using cell culture model
(North-West University (South-Africa), 2019)Since ancient times, wounds have been treated using plant based remedies. Of these remedies, Aloe species especially A. vera is probably the most prominent. Aloe vera is also the most studied of the Aloe genus in terms of ... -
Enhancing the solubility and in vitro permeability of pyrimethamine
(North-West University (South-Africa), 2021)ABSTRACT Malaria poses a substantial health problem, with nearly half of the world’s population susceptible to it. Malaria causes an estimated one million deaths per year. People who fall prey to malaria are also burdened ... -
In vitro evaluation of the efficacy of selected medicinal plant extracts against multidrug resistant cancer cells
(North-West University (South-Africa). Potchefstroom Campus, 2019)Cancer is ranked as one of the leading causes of death globally, and a significant number of these diagnosed malignancies are found in lung tissue. Small cell lung cancer (SCLC) is a high grade neuroendocrine cancer, which ... -
Pharmacokinetic interactions of Aloe vera gel polysaccharides with indinavir
(North-West University (South Africa) , Potchefstroom Campus, 2015)Aloe vera (L.) Burm.f. (Aloe barbadensis Miller) gel and whole leaf materials have shown the ability to modulate the bioavailability of vitamins and to change the transport of molecules across intestinal epithelia. In this ... -
Preparation and evaluation of multiple-unit solid oral dosage forms containing chemical permeation enhancing agents
(2014)The most popular and convenient route of drug administration remains the oral route, however, protein and peptide drugs such as insulin have poor membrane permeability and stability in the gastrointestinal tract. Absorption ... -
Transdermal penetration enhancement and clinical efficacy of Aloe marlothii and Aloe ferox compared to Aloe vera
(2014)Extensive research has already been performed on Aloe vera therefore it is important that researchers include other aloe species, such as Aloe marlothii and Aloe ferox, in studies involving aloe plant materials (Loots et ...