Browsing Health Sciences by Author "Zuma, N.H."
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Synthesis and anti-infective activities of novel nitrofurantoin derivatives
Zuma, N.H. (North-West University (South Africa), 2020)Tuberculosis (TB) continues to be in the top ten lethal diseases. In 2018, it was responsible for 1.5 million deaths. Mycobacterium tuberculosis (Mtb) is the bacterium responsible for TB infection in humans. It is estimated ... -
Synthesis and anti-leishmanial activity of novel 2,3-disubstituted-4(3H)-quinazolinone derivatives
Ralph, G.L. (North-West University (South Africa), 2020)Leishmaniasis is a disease resulting from the ingress of protozoan protists of the genus Leishmania (L.) into the mononuclear phagocytes of vertebrate hosts. These parasites are mainly transmitted by the haematophagous ... -
Synthesis and antileishmanial activity of novel benzothiadiazine-1,1-dioxide derivatives
Mangwegape, D.K. (North-West University (South-Africa), 2021)Leishmaniasis claims thousands of lives of the human populace every year. Globally, it infects approximately 12-15 million people annually and estimations have indicated that approximately more than 350 million people are ...