Browsing Health Sciences by Author "Wessels, J.C."
Now showing items 1-7 of 7
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The detection and quantification of biomolecules in biological sample matrices
Viljoen, Francois Petrus (North-West University (South-Africa), 2019)In the bodies of living humans and animals, endogenous biomolecules, and in particular the chemical messengers, play an essential role in the maintenance and functionality of physiological processes (Daintith, 2008; Gault ... -
The development and validation of HPLC methods for the detection of drug and detergent traces on laboratory glassware in a pharmaceutical laboratory
Mothobi, Pride Mmakeletso (North-West University, 2012)Pharmaceutical contract testing laboratories carry a responsibility to ensure that medicine made available for consumption by patients is of the approved quality for their intended health use. Glassware is an essential ... -
Development of a stability indicating HPLC method for the Pheroid™ delivery system
Van den Berg, Elaine (North-West University, 2010)Stability plays an important role in the development of a new drug product. High Performance Liquid Chromatography (HPLC) is considered a stability indicating method of analysis. It is widely used in the pharmaceutical ... -
Influence of particle size on solubility of active pharmaceutical ingredients
Lubbe, Elizabeth Cornelia (North-West University, 2012)The aqueous solubility of an active pharmaceutical ingredient (API) is an important property that requires evaluation during early development and prior to formulation of the final product. With general, experimental, ... -
Method development for extraction and HPLC analysis of kaempferol, chrysin and quercetin
Ludick, Nicolaas Johannes Jacobus (North-West University (South-Africa), 2020)Flavonoids (different phytochemical compounds found in plants acting as phytoalexins), have been found to have potent antioxidant effects. This has led into studies conducted on its effect on the body in reducing oxidative ... -
PheroidTM-based anti-malarial formulations : HPLC method development and stability studies
Pretorius, Marguerite (North-West University, 2008)Malaria remains one on the world's most common infectious diseases with 300 to 500 million cases every year. The current treatment of malaria is restricted due to ever increasing drug resistance, cost of treatment and the ... -
Stability of amorphous azithromycin in a tablet formulation
Obulapuram, Prasanna Kumar (2014)It is a well-known fact that drugs can exist in different solid-state forms. These solid-state forms can be either crystalline or amorphous. Furthermore, significant differences are identified between the different solid-state ...