Browsing Health Sciences by Author "Aucamp, M"
Now showing items 1-4 of 4
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Combined first line anti-TB drugs: new insights into stability
(North-West University (South-Africa). Potchefstroom Campus, 2019-05)Tuberculosis (TB) is the most prevalent infectious cause of death globally, affecting approximately one-third of the world’s population (Borgdoff et al., 2002). Mycobacterium tuberculosis (M. tuberculosis) is spread ... -
Investigation of the physico-chemical properties of amorphous solid-state forms of azithromycin
(North-West University (South Africa) , Potchefstroom Campus, 2016)Azithromycin is chemically modified from the macrolide, erythromycin and thereby shows improved efficacy and has more advantages above other macrolides. Azithromycin is currently the most prescribed and used macrolide ... -
Investigation of the stabilising effects of niosomes on the amorphous forms of roxithromycin
(North-West University (South Africa), Potchefstroom Campus, 2018)The first aim of this research study was to determine the effect of the excipients used in the typical niosome preparation on the solid-state nature of three solid-state forms of roxithromycin. The second aim was to ascertain ... -
The physico–chemical properties of the anti–tuberculosis drug ethionamide
(North-West University, 2012)Methods of recrystallisation from solution using various solvents as well as physical vapour deposition (PVD) methods were employed in an attempt to create different polymorphic forms of the anti-tuberculosis drug ...
