Browsing by Advisor/Supervisor
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Design, synthesis and biological evaluation of selected 7-azaindole derivatives and structurally related compounds as potential inhibitors of disease-related protein kinases
(North-West University (South-Africa), 2021)The bulk of the myriad cellular processes pertaining to normal cellular function in humans are governed by a superfamily of proteins known as protein kinases. Protein kinases account for 1.7% of all human genes and are ... -
Nitrothiazole-thiazolidinone hybrids : synthesis and in vitro antimicrobial evaluation
(North-West University (South-Africa), 2023)Tuberculosis (TB), caused by the bacterium Mycobacterium tuberculosis (Mtb), is one of the world’s most fatal infectious diseases. Annually, 10 million people fall ill with TB and 1.5 million people die from it globally. ... -
Synthesis and in vitro anti-tubercular evaluation of 6-nitroquinolone-3-carboxamides
(North-West University (South Africa), 2020)Tuberculosis (TB) is a disease that has been a major scourge of humankind since time immemorial. It is an airborne disease that mainly affects the lungs and it is caused by Mycobacterium tuberculosis (Mtb)─ a pathogenic ...