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The synthesis and evaluation of dual inhibitors of monoamine oxidase and catechol-O-methyltransferase
(North-West University (South Africa), Potchefstroom Campus, 2018)
Parkinson’s disease is the second most prevalent neurodegenerative disorder after Alzheimer’s disease. Parkinson’s disease is a debilitating, incurable, bradykinetic disorder which seriously inhibits a patient’s quality ...
Design, synthesis and evaluation of novel levodopa pro-drugs for the treatment of Parkinson's disease
(North-West University, 2018)
Parkinson's disease is a slowly progressive neurodegenerative disorder of unknown cause that selectively affects the dopaminergic, extrapyramidal nigrostriatal pathway. Parkinson's disease is a mid- or late life disease, ...