Search
Now showing items 1-3 of 3
The synthesis and evaluation of dual inhibitors of monoamine oxidase and catechol-O-methyltransferase
(North-West University (South Africa), Potchefstroom Campus, 2018)
Parkinson’s disease is the second most prevalent neurodegenerative disorder after Alzheimer’s disease. Parkinson’s disease is a debilitating, incurable, bradykinetic disorder which seriously inhibits a patient’s quality ...
Synthesis and evaluation of 3,4-Dihydro-3-methyl-2(1H)-quinazolinone derivatives as monoamine oxidase inhibitors
(North-West University, Potchefstroom Campus, 2018)
Parkinson’s disease (PD) is an age related neurodegenerative disorder. Loss of dopamine from the striatum is responsible for the motor symptoms of PD. This loss of dopamine is due to degeneration of the neurons of the ...
Design, synthesis and evaluation of quinazolinone analogues as monoamine oxidase inhibitors
(North-West University (South Africa), Potchefstroom Campus, 2018)
Parkinson’s disease (PD) is the second most common neurodegenerative disease after
Alzheimer’s disease, and it is estimated to affect approximately 1% of the population over the
age of 65. PD is characterised by non-motor ...