Browsing Electronic Theses and Dissertations (ETDs) by Subject "2-Aminopirimidiene"
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Aminopyrimidine derivatives as adenosine antagonists
(2013)Aims of this project - The aim of this study was to design and synthesise novel 2-aminopyrimidine derivatives as potential adenosine A1 and A2A receptor antagonists. Background and rationale - Parkinson’s disease is the ... -
Syntheses of chalcones and 2–aminopyrimidines and their evaluation as monoamine oxidase inhibitors and as adenosine receptor antagonists
(North-West University, 2013)Background and rationale - Parkinson’s disease is a neurodegenerative disorder characterised by reduced levels of dopamine in the brain. The cause of Parkinson's disease is still unknown; however several theories pertaining ...