Now showing items 1-3 of 3

    • Synthesis and antimalarial activity of ethylene glycol oligomeric ethers of artemisinin 

      Steyn, Minette; N’Da, David D.; Breytenbach, Jaco C.; Breytenbach, Wilma J.; Smith, Peter J.; Steyn, Minette; N’Da, David D.; Breytenbach, Jaco C.; Breytenbach, Wilma J.; Smith, Peter J. (Wiley, 2011)
      Objectives The aim of this study was to synthesize a series of ethylene glycol ether derivatives of the antimalarial drug artemisinin, determine their values for selected physicochemical properties and evaluate their ...
    • Synthesis and antimalarial activity of ethylene glycol oligomeric ethers of artemisinin 

      Steyn, Minette; N'Da, David D.; Breytenbach, Jaco C.; Breytenbach, Wilma J.; Smith, Peter J.; Meredith, Sandra (Wiley, 2011)
      Objectives The aim of this study was to synthesize a series of ethylene glycol ether derivatives of the antimalarial drug artemisinin, determine their values for selected physicochemical properties and evaluate their ...
    • Synthesis, antimalarial activity and cytotoxicity of 10-aminoethylether derivatives of artemisinin 

      Cloete, Theunis T.; Breytenbach, J. Wilma; Breytenbach, Jaco C.; N'Da, David D.; De Kock, Carmen; Smith, Peter J. (Elsevier, 2012)
      In this study, a series of 11 10-aminoethylether derivatives of artemisinin were synthesised and their antimalarial activity against both the chloroquine sensitive (D10) and resistant (Dd2) strains of Plasmodium falciparum ...