Browsing Faculty of Natural and Agricultural Sciences by Subject "African"
Now showing items 1-8 of 8
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The aetiology of cardiovascular disease: a role for mitochondrial DNA?
(Clinics Cardive Publishing, 2018)Cardiovascular disease (CVD) is a world-wide cause of mortality in humans and its incidence is on the rise in Africa. In this review, we discuss the putative role of mitochondrial dysfunction in the aetiology of CVD and ... -
An assessment of perceptions, sources and uses of water among six African communities in the North West Province of South Africa
(Water Research Commission, 2016)The aim of this study was to assess perceptions, sources and uses of water among African residents of six different impoverished communities in the North West Province (NWP) of South Africa. A sequential exploratory ... -
Baroreceptor sensitivity, cardiovascular responses and ECG left ventricular hypertrophy in men: the SABPA study
(Taylor & Francis, 2011)Aim. Research has shown a significant relationship between hypertension and attenuated baroreceptor sensitivity (BRS), which in turn reflects alterations of autonomic control of the cardiovascular system. The objective of ... -
Exploring the link between serum peroxides and angiogenesis in a bi-ethnic population from South Africa: the SAfrEIC study
(Elsevier, 2013)Background: Reactive oxygen species (ROS) play a fundamental role in angiogenesis, and in turn, angiogenic growth factors also affect ROS. Angiogenesis and ROS are intricately involved in vascular deterioration. Since ... -
Implementing a new variant load model to investigate the role of mtDNA in oxidative stress and inflammation in a bi-ethnic cohort: the SABPA study
(Taylor & Francis, 2019)Mitochondrial DNA (mtDNA) variation has been implicated in several common complex and degenerative diseases, including cardiovascular disease. Inflammation is seen as part of many of these conditions. Mitochondria feature ... -
Nocturnal blood pressure, 3–methoxy–4–hydroxyphenylglycol and carotid intima–media thickness: the SABPA study
(Elsevier, 2013)Background: Research demonstrated a significant relationship between elevated nocturnal blood pressure and sym-pathetic hyperactivity. The study aimed to investigate possible associations between norepinephrine ... -
Psychosocial health of an African group before awareness of HIV status: a comparative study
(Taylor & Francis, 2011)This study aimed to explore the psychosocial health profiles of people with and without HIV before they learned their infection status. A total of 1,025 participants (males = 386, females = 639, age range = between 32 and ... -
Using MutPred derived mtDNA load scores to evaluate mtDNA variation in hypertension and diabetes in a two-population cohort: the SABPA study
(Elsevier, 2017)Mitochondrial DNA (mtDNA) variation has been implicated in many common complex diseases, but inconsistent and contradicting results are common. Here we introduce a novel mutational load hypothesis, which also considers the ...