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The profile and development of the lower limb in Setswana-speaking children between the ages of 2 and 9 years
(MDPI, 2020)
Profile data on normal lower limb development and specifically tibiofemoral angle development in black, Setswana-speaking South African children are lacking. This study aimed to provide profiles on the development of the ...
Accumulation of TB-active compounds in murine organs relevant to infection by mycobacterium tuberculosis
(Frontiers Media, 2020)
Tuberculosis (TB), the leading cause of death due to an infectious agent, requires
prolonged and costly drug treatments. With the rise in incidence of MDR and XDR TB,
newer more efficacious treatments which are better ...
The new wave of Asia: a message from the president of the International Society of Hypertension
(Wiley, 2020)
Globally, raised blood pressure is the leading risk factor accountable for over 10.4 million deaths per year.1 The cardiovascular consequences of hypertension are devastating, which is why raised blood pressure requires ...
2020 International Society of Hypertension global hypertension practice guidelines
(AHA, 2020)
Context and Purpose of This Guideline
Statement of Remit
To align with its mission to reduce the global burden of raised
blood pressure (BP), the International Society of Hypertension
(ISH) has developed worldwide ...
Association of dairy consumption with metabolic syndrome, hypertension and diabetes in 147 812 individuals from 21 countries
(BMJ, 2020)
Objective Our aims were to assess the association of
dairy intake with prevalence of metabolic syndrome (MetS)
(cross-sectionally) and with incident hypertension and
incident diabetes (prospectively) in a large ...
Inflammation and salt in young adults: the African-PREDICT study
(Springer, 2020)
Purpose
Low-grade inflammation and a diet high in salt are both established risk factors for cardiovascular disease. High potassium (K+) intake was found to counter increase in blood pressure due to high salt intake and ...
National expenditure on health research in South Africa: how has the landscape changed in the past decade?
(Health & Medical Publishing Group, 2020)
Background. Over the past 18 years, the South African (SA) Ministry of Health has committed to allocate 2% of the national health budget to research, while the National Health Research Policy (2001) proposed that the health ...
Development of a self-emulsifying drug delivery system for optimized topical delivery of clofazimine
(MDPI, 2020)
A quality-by-design and characterization approach was followed to ensure development of
self-emulsifying drug delivery systems (SEDDSs) destined for topical delivery of the highly lipophilic
clofazimine. Solubility and ...
Replication and expansion of epigenomewide association literature in a black South African population
(BMC, 2020)
DNA methylation is associated with non-communicable diseases (NCDs) and related traits. Methylation data on continental African ancestries are currently scarce, even though there are known genetic and epigenetic differences ...
Trends in alcohol consumption in relation to cause-specific and all-cause mortality in the United States: a report from the NHANES linked to the US mortality registry
(Oxford Univ Press, 2020)
Background
Excessive alcohol use is the third leading cause of mortality in the United States, where alcohol use consistently increased over the last decades. This trend is currently maintained, despite regulatory policies ...