Search
Now showing items 11-13 of 13
Therapeutic potential of selectively targeting the α2c-adrenoceptor in cognition, depression, and schizophrenia: new developments and future perspective
(Frontiers Media, 2017)
α2A- and α2C-adrenoceptors (ARs) are the primary α2-AR subtypes involved in central nervous system (CNS) function. These receptors are implicated in the pathophysiology of psychiatric illness, particularly those associated ...
High sedentary behaviour and low physical activity are associated with anxiety and depression in Myanmar and Vietnam
(MDPI, 2019)
The study aimed to estimate independent and combined associations of sedentary behaviour and physical activity with anxiety and depression among chronic disease patients in Myanmar and Vietnam. The cross-sectional sample ...
A critical role of mitochondria in BDNF-associated synaptic plasticity after one-week vortioxetine treatment
(Oxford Univ Press, 2018)
Background
Preclinical studies have indicated that antidepressant effect of vortioxetine involves increased synaptic plasticity and promotion of spine maturation. Mitochondria dysfunction may contribute to the pathophysiological ...