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Now showing items 11-20 of 44
Prevalence of comorbidities in women with and without breast cancer in Soweto, South Africa: results from the SABC study
(HMPG, 2019)
Background. Comorbidities occurring concurrently in breast cancer patients can be burdensome, as they may negatively influence time and stage of presentation.
Objectives. To describe the comorbid health conditions among ...
Cultural coping as a risk for depression and hypertension: the SABPA prospective study
(Clinics Cardive, 2018)
Objectives: In past studies, a lack of social support has been associated with cardiovascular disease (CVD) risk, particularly in black Africans. However, whether or not coping strategies have beneficial effects on blood ...
Animal models of major depressive disorder and the implications for drug discovery and development
(Taylor & Francis, 2019)
Introduction: Depression is a highly debilitating psychiatric disorder that affects the global population and causes severe disabilities and suicide. Depression pathogenesis remains poorly understood, and the disorder is ...
An explorative study on the relationship between learning opportunities at school and at work and adolescents' mental health
(Ubiquity Press, 2020)
Based on the Job Demands-Resources model, this study examined the association of
learning opportunities of adolescents at school and work with their mental health,
operationalized in terms of life satisfaction and ...
Esketamine and rapastinel, but not imipramine, have antidepressant-like effect in a treatment-resistant animal model of depression
(Cambridge Univ Press, 2019)
Objectives:
Treatment-resistance to antidepressants is a major problem in the pharmacotherapy of major depressive disorder (MDD). Unfortunately, only a few animal models are suitable for studying treatment-resistant ...
High sedentary behavior is associated with depression among rural South Africans
(MDPI, 2019)
The study aimed to investigate the association between sedentary behavior and depression among rural South Africans. Data were analyzed from the cross-sectional baseline survey of the “Health and Aging in Africa: A ...
Electroconvulsive seizures regulates the Brd1 gene in the frontal cortex and hippocampus of the adult rat
(Elsevier, 2012)
Depressive disorders represent a significant health concern as they are associated with high social and
physical dysfunction and increased risk for suicide. Electroconvulsive therapy (ECT) is the most effective
treatment ...
Electroconvulsive seizures regulates the Brd1 gene in the frontal cortex and hippocampus of the adult rat
(Elsevier, 2012)
Depressive disorders represent a significant health concern as they are associated with high social and
physical dysfunction and increased risk for suicide. Electroconvulsive therapy (ECT) is the most effective
treatment ...
Isolation-induced behavioural changes in a genetic animal model of depression
(Elsevier, 2012)
Depression is a heterogeneous disorder displaying a range of symptoms including feelings of despair and social withdrawal. Social isolation may complicate the progression of depression and have effects on both behaviour ...
Efficacy of adjunctive Garcinia mangostana Linn (mangosteen) pericarp for bipolar depression: study protocol for a proof-of-concept trial
(ABP - Brazilian Psychiatric Association, 2019)
Objective: Bipolar depression is characterized by neurobiological features including perturbed oxidative
biology, reduction in antioxidant levels, and a concomitant rise in oxidative stress markers.
Bipolar depression ...