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The association of 25(OH)D with blood pressure, pulse pressure and carotid–radial pulse wave velocity in African women
(Public Library of Science, 2013)
High susceptibility of the African population to develop cardiovascular disease obliges us to investigate possible
contributing risk factors. Our aim was to determine whether low 25(OH)D status is associated with increased ...
Psychological distress and the development of hypertension over 5 years in Black South Africans
(Wiley–blackwell, 2015)
Alarming increases in the incidence of hypertension in many low– and middle–income countries are related to alcohol overuse. It is unclear whether alcohol overuse is a symptom of psychological distress. The authors ...
Exploring the link between cardiovascular reactivity and end–organ damage in African and Caucasian men: the SABPA study
(Oxford University Press, 2013)
BACKGROUND Heart failure in the African population is reaching alarming levels. Increased afterload as a result of increased vasoconstriction during stress may lead to impaired ventricular function and stroke volume (SV) ...
Extracellular matrix biomarker, Fibulin–1 and Its association with Soluble uPAR in a Bi-ethnic South African population: the SAfrEIC study
(Elsevier, 2015)
Background
Fibulin-1 and soluble urokinase-type plasminogen activator receptor (suPAR) emerged as mediators in the development of sclerotic disease. SuPAR along with C-reactive protein (CRP) and albumin delineate ...
Cornell product relates to albuminuria in hypertensive black adults independently of blood pressure: the SABPA study
(Elsevier, 2015)
Evidence of the relationship between left ventricular hypertrophy and urinary albumin excretion is contradictory and limited in black adults in whom hypertensive heart disease is common. We aimed to investigate the ...
Low testosterone and hyperkinetic blood pressure responses in a cohort of South African men: the SABPA study
(Taylor & Francis, 2013)
Hypertension (HT) and the metabolic syndrome are major problems in Africa. The role of sex hormones in the cardiovascular profile of black Africans in South Africa has not been studied. Our objective was to study the ...
South African and international reference values for lung function and its relationship with blood pressure in Africans
(Elsevier, 2015)
Background
In South Africa respiratory diseases are highly prevalent, with cardiovascular disease being a manifestation. However, international reference values for lung function are commonly used, which may not be ...
The relationship of nitric oxide synthesis capacity, oxidative stress, and albumin-to-creatinine ratio in black and white men: the SABPA study
(Springer, 2016)
Inadequate substrate availability and increased
nitric oxide synthase inhibitor levels attenuate nitric oxide
(NO) synthesis, whereas increased vascular oxidative
stress may lead to inactivation of NO. We compared
markers ...
The African prospective study on the early detection and identification of cardiovascular disease and hypertension (African-PREDICT): design, recruitment and initial examination
(Sage, 2019)
Background: Globally hypertension is stabilising, but in sub-Saharan Africa the incidence of hypertension remains on an
increase. Although this might be attributed to poor healthcare and ineffective antihypertensive ...
Dimethylarginines: their vascular and metabolic roles in Africans and Caucasians
(BioScintifica, 2010)
Objective
Alarming increases in hypertension and type 2 diabetes among Africans accentuate the need to identify factors that could serve as targets for prevention or treatment. In Caucasian populations, asymmetric ...